Article
Sarcopenia-related traits and coronary artery disease: a bi-directional Mendelian randomization study.
Aging - 16 Feb 2020
Liu Hui-Min, Zhang Qiang, Shen Wen-Di, Li Bo-Yang, Lv Wan-Qiang, Xiao Hong-Mei, Deng Hong-Wen
Abstract excerpt
Previous Mendelian randomization (MR) studies have yielded a conflicting causal relationship between sarcopenia and coronary artery disease (CAD), and lack the association of CAD with sarcopenia. We performed a bi-directional MR approach to clarify the causality and causal direction between sarcopenia-related traits and CAD. In stage 1 analysis, estimates of inverse variance weighting (IVW) and several...
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