Effect of handgrip on coronary artery disease and myocardial infarction: a Mendelian randomization study.

doi:10.1038/s41598-017-01073-z

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Article

Effect of handgrip on coronary artery disease and myocardial infarction: a Mendelian randomization study.

Scientific reports - 19 Apr 2017

Xu Lin, Hao Yuan Tao

Abstract excerpt

Observational studies have reported an association of handgrip strength with risk of cardiovascular disease. However, residual confounding and reverse causation may have influenced these findings. A Mendelian randomization (MR) study was conducted to examine whether handgrip is causally associated with cardiovascular disease. Two single nucleotide polymorphisms (SNPs), rs3121278 and rs752045, were used as the...

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PMID: 28424468
DOI: 10.1038/s41598-017-01073-z
PMCID: PMC5430422

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