Article
Next-generation sequencing in thymic epithelial tumors uncovered novel genomic aberration sites and strong correlation between TMB and MSH6 single nucleotide variations.
Cancer letters - 28 Apr 2020
Chen Kai, Che Jiaming, Zhang Xianfei, Jin Runsen, Xiang Jie, Han Dingpei, Sun Yonghua, Gong Ziying, Zhang Daoyun, Li Hecheng
Abstract excerpt
Thymic epithelial tumors (TET) including thymomas and thymic carcinomas are rare, but they are common primary tumors in the anterior mediastinum. The etiology and tumorigenesis of TET remain unclear. To better understand the novel aberrations of this rare tumor and provide more significant mutation sites for targeted therapy, we performed next-generation sequencing detection on 55 patients with TET. Our results...
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