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Article

Massively parallel sequencing identifies recurrent mutations in TP53 in thymic carcinoma associated with poor prognosis.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Feb 2015

Moreira Andre L, Won Helen H, McMillan Robert, Huang James, Riely Gregory J, Ladanyi Marc, Berger Michael F

Abstract excerpt

BACKGROUND: The characterization of the molecular alterations in thymic epithelial tumors may lead to a better understanding of tumorigenesis, new therapeutic targets, and biomarkers in these tumors. METHODS: Paired tissue (tumor and matched normal) from 15 thymic carcinomas (TCA) and six B3 thym...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25299233
DOI: 10.1097/JTO.0000000000000397

Genes

BCOR
BCL6
CYLD
SETD2
SMAD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25299233-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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