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Article

Transmission of NS5A-Inhibitor Resistance-Associated Substitutions Among Men Who Have Sex With Men Recently Infected with Hepatitis C Virus Genotype 1a.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 5 Nov 2020

Popping Stephanie, Verwijs Rosanne, Cuypers Lize, Claassen Mark A, van den Berk Guido E, De Weggheleire Anja, Arends Joop E, Boerekamps Anne, Molenkamp Richard, Koopmans Marion P, Verbon Annelies, Boucher Charles A B, Rijnders Bart J, van de Vijver David A M C

Abstract excerpt

The transmission of direct-acting antiviral resistance-associated substitutions (RAS) could hamper hepatitis C virus (HCV) cure rates and elimination efforts. A phylogenetic analysis of 87 men who have sex with men recently infected with HCV genotype 1a placed one-third (28/87) in a large cluster, in which 96% harbored NS5A M28V RAS.

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 32055843
DOI: 10.1093/cid/ciaa145
PMCID: PMC7643739

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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