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Article

Baseline NS5A resistance associated substitutions may impair DAA response in real-world hepatitis C patients.

Journal of medical virology - 1 Mar 2018

Carrasco Itzíar, Arias Ana, Benítez-Gutiérrez Laura, Lledó Gemma, Requena Silvia, Cuesta Miriam, Cuervas-Mons Valentín, de Mendoza Carmen

Abstract excerpt

Oral DAA have demonstrated high efficacy as treatment of hepatitis C. However, the presence of resistance-associated substitutions (RAS) at baseline has occasionally been associated with impaired treatment response. Herein, we examined the impact of baseline RAS at the HCV NS5A gene region on treatment response in a real-life setting. All hepatitis C patients treated with DAA including NS5A inhibitors at our...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28990680
DOI: 10.1002/jmv.24971

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