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Article

Pretreatment Hepatitis C Virus NS5A/NS5B Resistance-Associated Substitutions in Genotype 1 Uruguayan Infected Patients.

Disease markers - 1 Jan 2018

Aldunate Fabián, Echeverría Natalia, Chiodi Daniela, López Pablo, Sánchez-Cicerón Adriana, Fajardo Alvaro, Soñora Martín, Cristina Juan, Hernández Nelia, Moreno Pilar

Abstract excerpt

Hepatitis C Virus (HCV) infection treatment has dramatically changed with the advent of direct-acting antiviral agents (DAAs). However, the efficacy of DAAs can be attenuated by the presence of resistance-associated substitutions (RASs) before and after treatment. Indeed, RASs detected in DAA treatment-naïve HCV-infected patients could be useful for clinical management and outcome prediction. Although the...

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Identifiers

PMID: 30186532
DOI: 10.1155/2018/2514901
PMCID: PMC6112080

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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