Article
Maternal Larp6 controls oocyte development, chorion formation and elevation.
Development (Cambridge, England) - 26 Feb 2020
Hau Hoi Ting A, Ogundele Oluwaseun, Hibbert Andrew H, Monfries Clinton A L, Exelby Katherine, Wood Natalie J, Nevarez-Mejia Jessica, Carbajal M Alejandra, Fleck Roland A, Dermit Maria, Mardakheh Faraz K, Williams-Ward Victoria C, Pipalia Tapan G, Conte Maria R, Hughes Simon M
Abstract excerpt
La-related protein 6 (Larp6) is a conserved RNA-binding protein found across eukaryotes that has been suggested to regulate collagen biogenesis, muscle development, ciliogenesis, and various aspects of cell proliferation and migration. Zebrafish have two Larp6 family genes: larp6a and larp6b Viable and fertile single and double homozygous larp6a and larp6b zygotic mutants revealed no defects in muscle structure,...
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