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Proteomic-based identification of maternal proteins in mature mouse oocytes

3 Aug 2009

Abstract excerpt

BACKGROUND: The mature mouse oocyte contains the full complement of maternal proteins required for fertilization, reprogramming, zygotic gene activation (ZGA), and the early stages of embryogenesis. However, due to limitations of traditional proteomics strategies, only a few abundantly expressed proteins have yet been identified. Our laboratory applied a more effective strategy: one-dimensional sodium dodecyl...

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PMID: 19646285
DOI: 10.1186/1471-2164-10-348

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