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Article

Thy1 promoter activity in the Rosa26 locus in mice: lessons from Dre-rox conditional expression system.

Experimental animals - 5 Aug 2020

Tamura Saaki, Yasuoka Yukiko, Miura Hiromi, Takahashi Gou, Sato Masahiro, Ohtsuka Masato

Abstract excerpt

The pronuclear injection (PI)-based targeted transgenesis (PITT) method allows the generation of targeted transgenic (Tg) mice wherein a single copy of a transgene is integrated into the Rosa26 locus following PI. The Rosa26 locus allows unbiased ubiquitous expression of integrated transgenes; however, it remains little known whether tissue-specific promoters retain their functional properties when placed at the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 32051391
DOI: 10.1538/expanim.20-0002
PMCID: PMC7445056

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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