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Article

Restoration of FKBP51 protein promotes the progression of castration resistant prostate cancer

1 Dec 2019

Abstract excerpt

Background: As deregulation of androgen receptor (AR) signaling target genes is associated with tumorigenesis and the development of prostate cancer (PCa), AR signaling is the primary therapeutic target for PCa. Although patients initially responses to first-line androgen deprivation therapies (ADTs), most of them with advanced PCa progress to lethal castration-resistant prostate cancer (CRPC). Recent studies...

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PMID: 32042745
DOI: 10.21037/atm.2019.11.127

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