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Article

A high-resolution HLA imputation system for the Taiwanese population: a study of the Taiwan Biobank.

The pharmacogenomics journal - 1 Oct 2020

Huang Yu-Han, Khor Seik-Soon, Zheng Xiuwen, Chen Hsuan-Yu, Chang Ya-Hsuan, Chu Hou-Wei, Wu Pei-Ei, Lin Yu-Ju, Liao Shu-Fen, Shen Chen-Yang, Tokunaga Katsushi, Lee Mei-Hsuan

Abstract excerpt

An imputation algorithm for human leukocyte antigen (HLA) is helpful for exploring novel disease associations. However, population-specific HLA imputation references are essential for achieving high imputation accuracy. In this study, a subset of 1012 individuals from the Taiwan Biobank (TWB) who underwent both whole-genome SNP array and NGS-based HLA typing were used to establish Taiwanese HLA imputation...

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Source

Identifiers

PMID: 32042094
DOI: 10.1038/s41397-020-0156-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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