Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

A population-specific genomic reference panel for Taiwan: NHRI-RP-1.

Journal of biomedical science - 11 Aug 2026

Cheng Kuang-Huan, Chen Yi-Rong, Chung Ren-Hua, Lin Ming-Wei, Weng Hui-Ying, Lin Yuh-Ru, Lin Yung-Feng, Hsu Jacob Shujui, Kirby Ralph, Chuang Shao-Yuan, Liu Yu-Li, Huang Shiu-Feng Kathy, Chen Wei J, Hsu Chih-Cheng, Sheu Wayne Huey-Herng, Tsai Shih-Feng

Abstract excerpt

BACKGROUND: To enhance the efficiency of identifying rare variants within the Taiwanese population and to support genome-wide association studies (GWAS) and imputation studies for genetic risk prediction in the Han population, we have developed the National Health Research Institutes (NHRI) reference panel (NHRI-RP-1). METHODS: NHRI-RP-1 is based on 2,561 whole genome sequences taken from the in-house NHRI...

Topics

Join the communities discussing this publication.

DRD1 gene
Gene Frequency
MAF gene
Genome, Human
Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 42576224
DOI: 10.1186/s12929-026-01261-y
PMCID: PMC13459345

Genes

MAF
DRD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A population-specific genomic reference panel for Taiwan: NHRI-RP-1.PMID 42576224Read ↗

Population-specific reference panel improves imputation quality for genome-wide association studies conducted on the Japanese population.Semantic proximity Read ↗

The Taiwan Precision Medicine Initiative: A Cohort for Large-Scale StudiesSemantic proximity Read ↗

Complete genomic profiles of 1,496 Taiwanese reveal curated medical insightsSemantic proximity Read ↗

Rare variants discovery by extensive whole-genome sequencing of the Han Chinese population in Taiwan: Applications to cardiovascular medicine.Semantic proximity Read ↗

Next-generation sequencing analysis with a population-specific reference genomeSemantic proximity Read ↗

Population-Specific Polygenic Risk Scores Developed for the Han ChineseSemantic proximity Read ↗

Next-generation sequencing analysis with a population-specific human reference genome.Semantic proximity Read ↗

Whole-genome sequencing of 3,135 individuals representing the genetic diversity of the Japanese populationSemantic proximity Read ↗

Whole-genome reference panel of 1,781 Northeast Asians improves imputation accuracy of rare and low-frequency variantsSemantic proximity Read ↗

Human genetic variation database, a reference database of genetic variations in the Japanese population.Semantic proximity Read ↗

A High-resolution Haplotype-resolved Reference Panel Constructed from the China Kadoorie Biobank StudySemantic proximity Read ↗

NyuWa Genome resource: A deep whole-genome sequencing-based variation profile and reference panel for the Chinese population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.