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Exploring the biological hallmarks of cancer of unknown primary: where do we stand today?

11 Feb 2020

Abstract excerpt

Cancer of unknown primary (CUP) affects a small percentage of the general population. Nonetheless, a substantial number of these patients have a poor prognosis and consequently succumb to their illness within a year of diagnosis. The natural history of CUP is characterised by early metastasis from the unknown primary site, aggressive course and resistance to conventional chemotherapy. Unfortunately, the processes...

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PMID: 32042068
DOI: 10.1038/s41416-019-0723-z

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