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Article

Cancer of unknown primary-Epidemiological trends and relevance of comprehensive genomic profiling.

Cancer medicine - 1 Sept 2018

Binder Carmen, Matthes Katarina Luise, Korol Dimitri, Rohrmann Sabine, Moch Holger

Abstract excerpt

BACKGROUND: Cancer of unknown primary (CUP) is a distinct clinicopathological entity with poor prognosis, frequently resistant to chemotherapy. Comprehensive genomic profiling (CGP) by next-generation sequencing potentially identifies novel treatment options for CUP patients. The objective of this study was to determine incidence and survival trends and to discuss the value of CGP in CUP patients. METHODS:...

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Identifiers

PMID: 30019510
DOI: 10.1002/cam4.1689
PMCID: PMC6144156

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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