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Epigenetic age acceleration of cervical squamous cell carcinoma converged to human papillomavirus 16/18 expression, immunoactivation, and favourable prognosis

10 Feb 2020

Abstract excerpt

BACKGROUND: Ageing-associated molecular changes have been assumed to trigger malignant transformations and the epigenetic clock, and the DNA methylation age has been shown to be highly correlated with chronological age. However, the associations between the epigenetic clock and cervical squamous cell carcinoma (CSCC) prognosis, other molecular characteristics, and clinicopathological features have not been...

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Share to Cervical Cancer and HPV Research
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PMID: 32041662
DOI: 10.1186/s13148-020-0822-y

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