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DNA methylation age in paired tumor and adjacent normal breast tissue in Chinese women with breast cancer

30 Mar 2023

Abstract excerpt

BACKGROUND: Few studies have examined epigenetic age acceleration (AA), the difference between DNA methylation (DNAm) predicted age and chronological age, in relation to somatic genomic features in paired cancer and normal tissue, with less work done in non-European populations. In this study, we aimed to examine DNAm age and its associations with breast cancer risk factors, subtypes, somatic genomic profiles...

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PMID: 36991516
DOI: 10.1186/s13148-023-01465-1

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