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Article

The Personalisation of Glioblastoma Treatment Using Whole Exome Sequencing: A Pilot Study.

Genes - 6 Feb 2020

Garrett Anne-Marie, Lastakchi Sarah, McConville Christopher

Abstract excerpt

The molecular heterogeneity of glioblastoma has been linked to differences in survival and treatment response, while the development of personalised treatments may be a novel way of combatting this disease. Here we show for the first time that low passage number cells derived from primary tumours are greater than an 86% match genetically to the tumour tissue. We used these cells to identify eight genes that could...

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Identifiers

PMID: 32041307
DOI: 10.3390/genes11020173
PMCID: PMC7074406

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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