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HSPA1L rs1061581 polymorphism is associated with the risk of preeclampsia in Han Chinese women.

Bioscience reports - 28 Feb 2020

Zong Jinbao, Lin Yan, Tian Qingwu, Zhao Xin, Chu Kaiqiu, Jiang Bing, Li Shengjun, Sun Guirong, Liu Shiguo

Abstract excerpt

Preeclampsia (PE) is an excessive systemic inflammation response with dysfunction of endothelial. As a stress protein, heat shock protein 70 (HSP70) plays a pivotal role in protecting cells against apoptosis, oxidative damage and genetic damage. In humans, three genes encode members of the HSP70 class: HSPA1A, HSPA1B and HSPA1L. Our study was to investigate the association between genetic variations of HSPA1L and...

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Identifiers

PMID: 32039449
DOI: 10.1042/BSR20194307
PMCID: PMC7048671

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