Article
Associations between IGFBP1 gene polymorphisms and the risk of preeclampsia and fetal growth restriction.
Hypertension research : official journal of the Japanese Society of Hypertension - 1 Sept 2023
Peng Xianglan, He Dong, Peng Rui, Feng Jianyang, Chen Dunjin, Xie Hongkai, Li Qixuan, Guo Yitong, Zhou Jiaxiong, Chen Yang, He Hong
Abstract excerpt
IGFBP1 plays a critical role in the pathogenesis of preeclampsia (PE), but the association between single nucleotide polymorphism (SNP) of IGFBP1 gene and PE susceptibility has not yet been determined. In our study, 229 women with PE and 361 healthy pregnant (non-PE) women were enrolled to investigate its association via TaqMan genotyping assay. In addition, the protein levels of IGFBP1 under different genotypes...
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