Hypoxia-inducible factor-1α gene polymorphisms in early and late onset preeclampsia in Sinhalese women.

doi:10.1016/j.placenta.2014.04.008

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Article

Hypoxia-inducible factor-1α gene polymorphisms in early and late onset preeclampsia in Sinhalese women.

Placenta - 1 Jul 2014

Andraweera P H, Dekker G A, Thompson S D, Dissanayake V H W, Jayasekara R W, Roberts C T

Abstract excerpt

INTRODUCTION: Early (EPE) and late (LPE) onset preeclampsia are increasingly being recognized as two distinct disorders. Placental vascular defects are more common in EPE. Hypoxia Inducible Factor 1α (HIF1α) regulates the expression of many angiogenic growth factors in the placenta. We studied the association of two polymorphisms in the HIF1α gene (rs11549465 and rs10873142) with EPE and LPE. METHODS: 175...

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PMID: 24819156
DOI: 10.1016/j.placenta.2014.04.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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