Article
The variations in the IL1RL1 gene and susceptibility to preeclampsia.
Immunological investigations - 1 Jan 2014
Chen Peng, Zhang Kui, Zhou Bin, Zhang Zhu, Song Yaping, Pu Yan, Yang Yan, Zhang Yanyan, Zhou Rong, Wang Tao, Zhang Lin
Abstract excerpt
The IL1RL1, which encodes at least three isoforms by alternative splicing, has been identified to be involved in the initiation and perpetuation of inflammation. In spite of being a main contributor of maternal and perinatal mortality, the mechanism responsible for the pathophysiology of preeclampsia has not yet been well addressed. To investigate the relationship between IL1RL1 polymorphisms and preeclampsia...
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