Genetic susceptibility analysis of GCLC rs17883901 polymorphism to preeclampsia in Chinese Han women.

doi:10.1080/09513590.2020.1725970

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Genetic susceptibility analysis of GCLC rs17883901 polymorphism to preeclampsia in Chinese Han women.

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology - 1 Sept 2020

Li Jing, Yin Fanglian, Lin Yan, Gao Ming, Wang Ling, Liu Shiguo, Song Weiqing, Ye Yuanhua

Abstract excerpt

Preeclampsia (PE) is a specific obstetric disorder that may result in maternal and neonatal morbidity and mortality. Increasing evidence has been indicated that some candidate genes related to oxidative stress, such as glutamate-cysteine ligase, catalytic subunit (GCLC), glutamate-cysteine ligase, modifier subunit (GCLM), involve in the pathogenesis of PE. After the genetic contribution of GCLC rs17883901...

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PMID: 32054366
DOI: 10.1080/09513590.2020.1725970

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