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Gene polymorphisms and motor levodopa-induced complications in Parkinson's disease.

Brain and behavior - 1 Mar 2020

Michałowska Małgorzata, Chalimoniuk Małgorzata, Jówko Ewa, Przybylska Iwona, Langfort Józef, Toczylowska Beata, Krygowska-Wajs Anna, Fiszer Urszula

Abstract excerpt

OBJECTIVE: The aim of the study was to evaluate the association of individual and combined single-nucleotide polymorphisms in brain-derived neurotrophic factor (BDNF), dopamine transporter (DAT), and catechol-O-methyltransferase (COMT) genes with the occurrence of motor levodopa-induced complications (MLIC) in Parkinson's disease (PD). MATERIALS AND METHODS: We studied 76 patients with PD (MLIC occurred in 56.6%)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32022467
DOI: 10.1002/brb3.1537
PMCID: PMC7066344

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