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Article

The role of genetic factors in the occurrence of levodopa-induced motor complications in Parkinson's disease.

Neurological research - 1 Mar 2026

Radojević Branislava, Milovanović Andona, Petrović Igor, Svetel Marina, Marjanović Ana, Jančić Ivan, Stanisavljević Dejana, Milićević Ognjen, Savić Miroslav M, Kostić Vladimir S, Dragašević-Mišković Nataša T

Abstract excerpt

BACKGROUND: The genetic contribution to the development of levodopa-induced motor complications in Parkinson's disease (PD) remains poorly understood. OBJECTIVES: We aimed to investigate the association between selected polymorphisms of the catechol-O-methyltransferase (COMT), dopamine receptor D2 (DRD2), ankyrin repeat and kinase domain containing 1 (ANKK1) and dopamine transporter (DAT) genes and the occurrence...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dopamine Plasma Membrane Transport Proteins

Share to Dyskinesia, Drug-Induced

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Source

Identifiers

PMID: 40632937
DOI: 10.1080/01616412.2025.2528974

Genes

COMT
DRD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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