Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

High PD‑L1 expression drives glycolysis via an Akt/mTOR/HIF‑1α axis in acute myeloid leukemia

23 Jan 2020

Abstract excerpt

Acute myeloid leukemia (AML) is a hematological malignancy derived from immature myeloid cells, which have the characteristics of abnormal proliferation and differentiation. Glycolysis has been a popular topic of research in recent years, with increasing uptake and consumption of glucose. The present study aimed to investigate the glycolysis of tumor cells in patients with AML; in particular, how programmed cell...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Myeloid Leukemia Research
Share to Cancer, Hypoxia, and Metabolism
Share to Neuroblastoma Research and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32020232
DOI: 10.3892/or.2020.7477

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

High PD‑L1 expression drives glycolysis via an Akt/mTOR/HIF‑1α axis in acute myeloid leukemiaPMID 32020232Read ↗

PGK1, a promising biomarker and therapeutic target for patients with acute myeloid leukemia who are susceptible to disease relapseSemantic proximity Read ↗

The Glycolytic Gatekeeper PDK1 defines different metabolic states between genetically distinct subtypes of human acute myeloid leukemia.Semantic proximity Read ↗

Advances in pathogenesis research and challenges in treatment development for acute myeloid leukemia.Semantic proximity Read ↗

PD-L1 regulates cell proliferation and apoptosis in acute myeloid leukemia by activating PI3K-AKT signaling pathwaySemantic proximity Read ↗

Glycolytic Enzyme PKM2 Mediates Autophagic Activation to Promote Cell Survival in NPM1-Mutated LeukemiaSemantic proximity Read ↗

TIGAR cooperated with glycolysis to inhibit the apoptosis of leukemia cells and associated with poor prognosis in patients with cytogenetically normal acute myeloid leukemiaSemantic proximity Read ↗

A Comprehensive Metabolism-Related Gene Signature Predicts the Survival of Patients with Acute Myeloid LeukemiaSemantic proximity Read ↗

Anti-Tumor Effects of BDH1 in Acute Myeloid LeukemiaSemantic proximity Read ↗

MiR-652-5p elevated glycolysis level by targeting TIGAR in T-cell acute lymphoblastic leukemiaSemantic proximity Read ↗

High Expression of CPT1A Predicts Adverse Outcomes: A Potential Therapeutic Target for Acute Myeloid LeukemiaSemantic proximity Read ↗

A Novel Therapeutic Target, BACH1, Regulates Cancer MetabolismSemantic proximity Read ↗

Upregulation of Glutamic-Oxaloacetic Transaminase 1 Predicts Poor Prognosis in Acute Myeloid LeukemiaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.