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Article

Decreased ovarian function and autophagy gene methylation in aging rats

3 Feb 2020

Abstract excerpt

BACKGROUND: Degeneration of ovarian function is an obvious feature of female aging. In addition, studies have shown that autophagy decreases with age, and DNA methylation is a hallmark epigenetic pattern during aging. However, it is not clear whether the expression and DNA methylation of autophagy genes are involved in the declines in ovarian function that occur during aging. RESULTS: levels and the mRNA and...

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Share to Autophagy in Disease and Therapy
Share to Epigenetics and DNA Methylation
Share to Genetics, Aging, and Longevity in Model Organisms

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PMID: 32014030
DOI: 10.1186/s13048-020-0615-0

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