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Article

The Autophagy Gene Atg16L1 is Necessary for Endometrial Decidualization.

Endocrinology - 1 Jan 2020

Oestreich Arin K, Chadchan Sangappa B, Popli Pooja, Medvedeva Alexandra, Rowen Marina N, Stephens Claire S, Xu Ran, Lydon John P, Demayo Francesco J, Jungheim Emily S, Moley Kelle H, Kommagani Ramakrishna

Abstract excerpt

Uterine receptivity is critical for establishing and maintaining pregnancy. For the endometrium to become receptive, stromal cells must differentiate into decidual cells capable of secreting factors necessary for embryo survival and placental development. Although there are multiple reports of autophagy induction correlated with endometrial stromal cell (ESC) decidualization, the role of autophagy in...

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Identifiers

PMID: 31875883
DOI: 10.1210/endocr/bqz039
PMCID: PMC6986551

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