NK cell‑produced IFN‑γ regulates cell growth and apoptosis of colorectal cancer by regulating IL‑15

Abstract excerpt

Globally, colorectal cancer (CC) is the third leading cause of mortality associated with cancer. Natural killer (NK) cells are a major class of cells that are responsible for eliminating tumor cells and cytokine production. NK cell‑mediated production of interferon gamma (IFN‑γ) has antiviral, immunoregulatory and anti‑tumor properties. IL‑15 is important in linking inflammation with cancer. For instance, IL‑15...

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