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Article

Identification of FOXH1 mutations in patients with sporadic conotruncal heart defect.

Clinical genetics - 1 Apr 2020

Wei Wei, Li Bojian, Li Fen, Sun Kun, Jiang Xuechao, Xu Rang

Abstract excerpt

Conotruncal heart defects (CTD) are an important subtype of congenital heart disease that occur due to abnormality in the development of the cardiac outflow tract (OFT). FOXH1 is a transcription factor that participates in the morphogenesis of the right ventricle and OFT. In this study, we confirmed the expression of FOXH1 in mouse and human embryos during OFT development. We also scanned the coding exons and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 32003456
DOI: 10.1111/cge.13710

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