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Article

HAND1 loss-of-function mutation contributes to congenital double outlet right ventricle.

International journal of molecular medicine - 1 Mar 2017

Li Li, Wang Juan, Liu Xing-Yuan, Liu Hua, Shi Hong-Yu, Yang Xiao-Xiao, Li Ning, Li Yan-Jie, Huang Ri-Tai, Xue Song, Qiu Xing-Biao, Yang Yi-Qing

Abstract excerpt

Congenital heart defects (CHDs), a wide variety of developmental abnormalities in the structures of the heart and the great thoracic blood vessels, are the most common form of birth defect in humans worldwide. CHDs are accountable for substantial morbidity and are still the leading cause of birth defect‑related deaths. Recent studies have demonstrated the pivotal roles of genetic defects in the pathogenesis of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28112363
DOI: 10.3892/ijmm.2017.2865

Genes

HAND1
GATA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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