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Article

Identification of ZFPM2 mutations in sporadic conotruncal heart defect patients.

Molecular genetics and genomics : MGG - 1 Feb 2018

Pu Tian, Liu Yang, Xu Rang, Li Fen, Chen Sun, Sun Kun

Abstract excerpt

Conotruncal heart defects (CTDs) are a group of cardiac malformations that involve outflow tract anomalies and the arterial pole of the heart. Recent reports have identified mutations in a number of genes associated with CTDs in human and animal models. ZFPM2 plays a role in cardiac development by acting as a transcriptional cofactor that interacts with GATA4. Because ZFPM2 was found to be important for cardiac...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Heart Defects, Congenital

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Source

Identifiers

PMID: 29018978
DOI: 10.1007/s00438-017-1373-6

Genes

ZFPM2
GATA4

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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