Article
How good are comparative models in the understanding of protein dynamics?
Proteins - 1 Jul 2020
Yazhini Arangasamy, Srinivasan Narayanaswamy
Abstract excerpt
The 3D structure of a protein is essential to understand protein dynamics. If experimentally determined structure is unavailable, comparative models could be used to infer dynamics. However, the effectiveness of comparative models, compared to experimental structures, in inferring dynamics is not clear. To address this, we compared dynamics features of ~800 comparative models with their crystal structures using...
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