Article
Diversity and motif conservation in protein 3D structural landscape: exploration by a new multivariate simulation method.
Journal of molecular modeling - 2 Mar 2018
Joshi Rajani R
Abstract excerpt
In this paper, diversity and conservation in the 'landscape' of random variation of protein tertiary structures are explored for quantitative feature-vector models of major types of functionally important 3D structural motifs. For this, I have deployed a recently developed nonparametric regression (NPR)-based multidimensional copula method of simulation. Apart from improved accuracy of multidimensional random...
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