Article
Increased chromosomal imbalances in recurrent pituitary adenomas.
Acta neuropathologica - 1 Dec 2001
Rickert C H, Dockhorn-Dworniczak B, Busch G, Moskopp D, Albert F K, Rama B, Paulus W
Abstract excerpt
Eight pituitary adenomas (four gonadotroph cell adenomas, three prolactin cell adenomas, one null cell adenoma) and their respective recurrences in the same patients were studied by comparative genomic hybridization. Chromosomal imbalances were found in seven of eight patients affecting two of eight primary and seven of eight recurrent tumors. Overall, pituitary adenomas showed an average of 1.6 chromosomal...
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