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Article

Driver mutations in ADGRL3 are involved in the evolution of ependymoma.

Laboratory investigation; a journal of technical methods and pathology - 1 Jul 2022

Wang Jing, Xi Shao-Yan, Zhao Qi, Xia Yun-Fei, Yang Qun-Ying, Cai Hai-Ping, Wang Fang, Zhao Yi-Ying, Hu Huan-Jing, Yu Zhi-Hui, Chen Fu-Rong, Xu Peng-Fei, Xu Ri-Zhen, Wang Jian, Zhang Ji, Ke Chao, Zhang Xiang-Heng, Lin Fu-Hua, Guo Cheng-Cheng, Lv Yan-Chun, Li Cong, Xie Hai-Tao, Cui Qian, Wu Hong-Mei, Liu Yan-Hui, Li Zhi, Su Hong-Kai, Zeng Jing, Han Fu, Li Zhao-Jie, Sai Ke, Chen Zhong-Ping

Abstract excerpt

Although there have been recent advances in the molecular pathology of ependymomas, little is known about the underlying molecular evolution during its development. Here, we assessed the clinical, pathological and molecular evolutionary process of ependymoma recurrence in a 9-year-old patient who had seven recurrences of supratentorial ependymoma and died from intracranial multiregional recurrences at the age of...

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Child
Ependymoma
Mutation
Receptors, G-Protein-Coupled

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35013530
DOI: 10.1038/s41374-021-00721-3

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