Article
Pituispheres Contain Genetic Variants Characteristic to Pituitary Adenoma Tumor Tissue.
Frontiers in endocrinology - 1 Jan 2020
Peculis Raitis, Mandrika Ilona, Petrovska Ramona, Dortane Rasma, Megnis Kaspars, Nazarovs Jurijs, Balcere Inga, Stukens Janis, Konrade Ilze, Pirags Valdis, Klovins Janis, Rovite Vita
Abstract excerpt
The most common type of pituitary neoplasms is benign pituitary adenoma (PA). Clinically significant PAs affect around 0.1% of the population. Currently, there is no established human PA cell culture available and when PA tumor cells are cultured they form two distinct types depending on culturing conditions either free-floating aggregates also known as pituispheres or cells adhering to the surface of cell plates...
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