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Article

Genetic variations in the sodium balance-regulating genes ENaC, NEDD4L, NDFIP2 and USP2 influence blood pressure and hypertension.

Kidney & blood pressure research - 1 Jan 2010

Jin Hyun-Seok, Hong Kyung-Won, Lim Ji-Eun, Hwang Sue-Yun, Lee Sang-Ho, Shin Chol, Park Hun Kuk, Oh Bermseok

Abstract excerpt

BACKGROUND/AIMS: In humans, the kidneys regulate blood pressure by balancing sodium concentrations. Fine-tuning of renal sodium reabsorption and excretion depends on the epithelial sodium channel protein (ENaC: protein complex of SCNN1A, SCNN1B, and SCNN1G). The surface expression of ENaC compone...

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Source

Identifiers

PMID: 20090362
DOI: 10.1159/000275706

Genes

NDFIP2
USP2
SGK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-20090362-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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