Article
The O-Antigen Epitope Governs Susceptibility to Colistin in Salmonella enterica.
mBio - 28 Jan 2020
Ricci Vito, Zhang Dexian, Teale Christopher, Piddock Laura J V
Abstract excerpt
Group D and group B Salmonella enterica serovars differ in their susceptibility to colistin with the former frequently intrinsically resistant (MIC > 2 μg/ml); however, the mechanism has not been described. Here, we show that the O-antigen epitope in group D Salmonella governs the levels of colistin susceptibility. Substitution of the rfbJ gene in a group B Salmonella with the rfbSE genes from a group D...
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