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Article

Patterning mechanisms diversify neuroepithelial domains in the Drosophila optic placode.

PLoS genetics - 1 Apr 2018

Mishra Abhishek Kumar, Bernardo-Garcia F Javier, Fritsch Cornelia, Humberg Tim-Henning, Egger Boris, Sprecher Simon G

Abstract excerpt

The central nervous system develops from monolayered neuroepithelial sheets. In a first step patterning mechanisms subdivide the seemingly uniform epithelia into domains allowing an increase of neuronal diversity in a tightly controlled spatial and temporal manner. In Drosophila, neuroepithelial patterning of the embryonic optic placode gives rise to the larval eye primordium, consisting of two photoreceptor (PR)...

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Identifiers

PMID: 29677185
DOI: 10.1371/journal.pgen.1007353
PMCID: PMC5937791

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Source receipt: pubmed, retrieved 7 Sept 2026.

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