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Article

Single-cell transcriptomics from human pancreatic islets: sample preparation matters

1 Jan 2019

Abstract excerpt

Single-cell RNA sequencing (scRNA-seq) of human primary tissues is a rapidly emerging tool for investigating human health and disease at the molecular level. However, optimal processing of solid tissues presents a number of technical and logistical challenges, especially for tissues that are only available at autopsy, which includes pancreatic islets, a tissue that is highly relevant to diabetes. To assess the...

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PMID: 31984226
DOI: 10.1093/biomethods/bpz019

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