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Article

SENP1 is a crucial promotor for hepatocellular carcinoma through deSUMOylation of UBE2T.

Aging - 22 Jan 2020

Tao Yifeng, Li Ruidong, Shen Conghuan, Li Jianhua, Zhang Quanbao, Ma Zhenyu, Wang Feifei, Wang Zhengxin

Abstract excerpt

The cooperative roles of SENP1 and UBE2T in development and progression of hepatocellular carcinoma (HCC) are still unknown. The expression levels of SENP1 and UBE2T were evaluated in clinical specimens and HCC cells. The relationship between clinicopathological features and SENP1 were analyzed. We constructed the HepG2-SENP1 knockout cell model and explored the functions of SENP1 and UBE2T in HCC development....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 31969492
DOI: 10.18632/aging.102700
PMCID: PMC7053586

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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