Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

UBE2C functions as a potential oncogene by enhancing cell proliferation, migration, invasion, and drug resistance in hepatocellular carcinoma cells

26 Mar 2019

Abstract excerpt

Abstract Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related mortality worldwide. Recently, ubiquitin-conjugating enzyme E2C (UBE2C) has been reported to be overexpressed in human cancers and act as a potential oncogene. However, little is known about the functional roles of UBE2C in HCC progression. In the present study, analysis of UBE2C mRNA expression in The Cancer Genome Atlas (TCGA)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hepatitis B Virus Studies
Share to RNA modifications and cancer
Share to Ubiquitin and proteasome pathways

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30914455
DOI: 10.1042/bsr20182384

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

UBE2C functions as a potential oncogene by enhancing cell proliferation, migration, invasion, and drug resistance in hepatocellular carcinoma cellsPMID 30914455Read ↗

Identification of the potential therapeutic target gene UBE2C in human hepatocellular carcinoma: An investigation based on GEO and TCGA databasesSemantic proximity Read ↗

UBE2S enhances the ubiquitination of p53 and exerts oncogenic activities in hepatocellular carcinomaSemantic proximity Read ↗

Depletion of UBE2C reduces ovarian cancer malignancy and reverses cisplatin resistance via downregulating CDK1Semantic proximity Read ↗

Ubiquitin-conjugating enzyme 2C (UBE2C) plays as a cancer diagnostic and prognostic marker: A Bioinformatics pan-cancer analysisSemantic proximity Read ↗

Upregulation of UBE2Q1 via gene copy number gain in hepatocellular carcinoma promotes cancer progression through β‐catenin‐EGFR‐PI3K‐Akt‐mTOR signaling pathwaySemantic proximity Read ↗

A Comprehensive Bioinformatics Analysis of UBE2C in CancersSemantic proximity Read ↗

Bioinformatics-based pan-cancer analysis of UBE2CSemantic proximity Read ↗

UBE2L3, a susceptibility gene that plays oncogenic role in hepatitis B-related hepatocellular carcinoma.Semantic proximity Read ↗

UBE2C is overexpressed in ESCC tissues and its abrogation attenuates the malignant phenotype of ESCC cell lines.Semantic proximity Read ↗

Increased expression of UBE2T predicting poor survival of ovarian cancer: based on comprehensive analysis of UBE2s, clinical samples and the GEO databaseSemantic proximity Read ↗

Identification of overexpressed genes in hepatocellular carcinoma, with special reference to <i>ubiquitin‐conjugating enzyme E2C</i> gene expressionSemantic proximity Read ↗

The interplay of UBE2T and Mule in regulating Wnt/β-catenin activation to promote hepatocellular carcinoma progressionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.