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AdipoRon , a new therapeutic prospect for Duchenne muscular dystrophy

21 Jan 2020

Abstract excerpt

BACKGROUND: Adiponectin (ApN) is a hormone known to exhibit insulin-sensitizing, fat-burning, and anti-inflammatory properties in several tissues, including the skeletal muscle. Duchenne muscular dystrophy (DMD) is a devastating disease characterized by dystrophin deficiency with subsequent chronic inflammation, myofiber necrosis, and impaired regeneration. Previously, we showed that transgenic up-regulation of...

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PMID: 31965757
DOI: 10.1002/jcsm.12531

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