Article
Association between the RAGE (receptor for advanced glycation end-products) -374T/A gene polymorphism and diabetic retinopathy in T2DM.
Revista da Associacao Medica Brasileira (1992) - 1 Nov 2017
Tao Dan, Mai Xuancheng, Zhang Tiesong, Mei Yan
Abstract excerpt
OBJECTIVE: Interaction between advanced glycation end-products (AGEs) and receptor for AGEs (RAGE) in cells could affect both extracellular and intracellular structure and function, which plays a pivotal role in diabetic microvascular complications. The results from previous epidemiological studies on the association between RAGE gene -374T/A polymorphism and diabetic retinopathy (DR) risk were inconsistent....
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