Article
Tripartite factors leading to molecular divergence between human and murine smooth muscle.
PloS one - 1 Jan 2020
Lee Soo Jung, Blanchett-Anderson Sabrina, Keep Simon G, Gasche Mitchell B, Wang Michael M
Abstract excerpt
A large number of pre-clinical and developmental investigations involve experimental vertebrate animals, of which mice have emerged as a favored organism. Recognition of the differences between humans and mice is essential for assessment of the relevance of animal studies to humans. The primary purpose of this study was to gauge the conservation between human and mouse vascular smooth muscle cell (VSMC) proteins...
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