Article

Evaluation of Five Mammalian Models for Human Disease Research Using Genomic and Bioinformatic Approaches

2023-05-26

Abstract excerpt

The suitability of an animal model to study human diseases heavily relies on the similarity between the two species at the genetic, epigenetic, gene expression and metabolic levels. However, consistent data from different animal models at each level to evaluate this suitability is lacking. With the availability of genome sequences for many mammalian species it is now possible to compare animal models based on the...

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Literature Corpus work: 0760a7fb-e38b-5a84-b95b-d15ed718b1ad
DOI: 10.20944/preprints202305.1816.v1

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