Article
Robust kernel association testing (RobKAT).
Genetic epidemiology - 1 Apr 2020
Martinez Kara, Maity Arnab, Yolken Robert H, Sullivan Patrick F, Tzeng Jung-Ying
Abstract excerpt
Testing the association between single-nucleotide polymorphism (SNP) effects and a response is often carried out through kernel machine methods based on least squares, such as the sequence kernel association test (SKAT). However, these least-squares procedures are designed for a normally distributed conditional response, which may not apply. Other robust procedures such as the quantile regression kernel machine...
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