Article
Genetic variation of the ATP-binding cassette transporter A1 and susceptibility to coronary heart disease.
Molecular genetics and metabolism - 1 May 2011
Jiang Zhihui, Zhou Rujuan, Xu Caixia, Feng Guangzhi, Zhou Yafeng
Abstract excerpt
ATP-binding cassette transporter A1 (ABCA1) is a member of a superfamily of membrane proteins that has attracted considerable attention as a candidate gene for coronary heart disease (CHD) based on its enzyme function as a key factor in regulating plasma HDL-C and apo A-I metabolism. It has been suggested that polymorphisms in the ABCA1 gene are risk factors for CHD, but a large number of studies have reported...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
