Article
Associations between common polymorphisms of adenosine triphosphate-binding cassette transporter A1 and coronary artery disease in a Tunisian population.
Archives of cardiovascular diseases - 1 Oct 2010
Rejeb Jihène, Omezzine Asma, Rebhi Lamia, Boumaiza Imen, Kchock Kaouthar, Belkahla Radhia, Rejeb Nabila Ben, Nabli Naoufel, Abdelaziz Ahmed Ben, Boughzala Essia, Bouslama Ali
Abstract excerpt
BACKGROUND: The adenosine triphosphate-binding cassette transporter A1 (ABCA1) protein plays an important role in the first step of the reverse cholesterol transport system. AIMS: We studied the association of four polymorphisms in the ABCA1 gene (G1051A, G2706A, G2868A and -565C/T) with lipid profile and coronary artery disease. METHODS: Overall, 316 Tunisian patients underwent coronary angiography. Genotyping...
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